TRANSMEMBRANE HELICES ARE AN OVER-PRESENTED AND EVOLUTIONARILY CONSERVED SOURCE OF MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I AND II EPITOPES

Transmembrane Helices Are an Over-Presented and Evolutionarily Conserved Source of Major Histocompatibility Complex Class I and II Epitopes

Cytolytic T cell responses are predicted to be biased towards membrane proteins.The peptide-binding grooves of most alleles of histocompatibility complex class I (MHC-I) are relatively hydrophobic, therefore peptide fragments derived from human transmembrane helices (TMHs) are predicted to be presented more often as would be expected based on their

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Exploring Trends and Gaps in Teaching Linguistics Research among Undergraduate EFL Students: A Bibliometric Analysis

The importance of linguistics is not just for EFL teachers to assist in mastering the concept of teaching.However, the understanding of linguistics should be started with the introductory for EFL Students as a fundamental course to help them build their understanding regarding what they are studying including the trends and gaps of the study in tha

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Galactic Evolution Showing a Constant Circulating Speed of Stars in a Galactic Disc without Requiring Dark Matter

It is an unsolved mystery that the rotation velocity of a galactic disc is same at any radial distances.The presence of dark matter is expected, but not observed.Here we propose a novel scheme for the evolution of the initial cosmic energy to current galaxies.According to the energy circulation theory, which we previously reported, the fundamental

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Amundsen Sea Embayment ice-sheet mass-loss predictions to 2050 calibrated using observations of velocity and elevation change

Mass loss from the Amundsen Sea Embayment of the West Antarctic Ice Sheet is a major chicago skyline graffiti contributor to global sea-level rise (SLR) and has been increasing over recent decades.Predictions of future SLR are increasingly modelled using ensembles of simulations within which model parameters and external forcings are varied within

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